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Clomipramine is an antidepressant taken orally that is primarily used to treat obsessive-compulsive disorder (OCD) in adolescents and adults. It relieves recurring unwanted thoughts that are beyond the person’s control, and repetitive behaviors or mental acts that a person with OCD may feel compelled to perform in order to ‘undo’ the obsessive thought. It is not considered a controlled substance by the FDA.

Other names for this medication:
Clomipramine, Anafranil, Clofranil, Clomipramina, Clora, Zenil,

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Clomipramine is used to treat obsessive compulsive disorder (OCD). OCD is a nervous condition wherein a person has recurring thoughts or ideas or does repetitive things because they are anxious.

Clomipramine is a tricyclic antidepressant (TCA). It is thought to work in the brain by increasing the activity of the chemical serotonin.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

  • Capsule

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Bcs1p, an AAA-family member, is a chaperone for the assembly of the cytochrome bc(1) complex. This allows use on a healthy tooth and on a tooth for which prosthodontic treatment has already been completed.

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This article considers the problem of identifying patients in one or more heterogeneous personal databases. The impact of political conflict on women: the case of Afghanistan. Beliefs about angina were significantly associated with functional and psychological status. Although the physiological importance of these effects is not clear, it is important to be aware of any potentially toxic activity in the B subunit, given that it has been proposed for use in a vaccine.

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Specific ultrastructural features and protein-synthesizing and proliferative activity of light and dark cells were demonstrated using data of electron radioautography. This past year has produced determinations of X-ray crystal structures for three metallo-beta-lactamases and the elucidation of the catalytic mechanisms for a monozinc and a dizinc enzyme. mucilaginosa, where no polymorphisms were observed in the strains tested. To assess whether examination of the bite marks could be useful for the differential diagnosis between venomous and nonvenomous snakebite.

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Inhibitory effect of prostaglandin F2 alpha on oxytocin release and on milk ejection in lactating rats. The effect of oral contraceptives (OCs) on Vitamins-B6, -B12, and folic acid metabolism was studied in a large population of women.

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Optokinetic eye movements are crucial for keeping a stable image on the retina during movements of the head. It is suggested that the right dominant transverse-sigmoid sinuses are partially occluded by tentorial meningioma, developing the dural arteriovenous fistula of the right transverse sinus.

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Relationships Between Adipokine Profiles, Physique Index, and Severity of Bronchiolitis in Infancy. Thus, skilled control of voluntary attention may allow anxious persons to limit the impact of threatening information.

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Perioperative Strokes Following Surgical Correction of Mitral Valves: A Systematic Review and Meta-Analysis. Immediately after, the first set of saliva specimens (S1) was collected over a period of 1 min to measure cortisol levels.

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This model may by useful in future experiments using sustained release formulations of hGH, and possibly for other compounds that may induce antibody production in pigs. Using a specific and sensitive fluorometric assay, the H2O2 release from as few as 2 X 10(5) mouse peritoneal macrophages could be detected continuously and quantitated. An oestrone-cytostatic compound was extractable from the liver half an hour after the injection of Estracyt.

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Close comparison revealed that the behavior of nE alpha molecules during cytokinesis was quite different from that of intact E-cadherin, and that the intercellular motility, i.e., the cell movement in a confluent sheet, was significantly suppressed in nE alpha transfectants although it was facilitated in E-cadherin transfectants. Analysis of quality of life before and after heart transplantation.

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Familial Parkinson mutant alpha-synuclein causes dopamine neuron dysfunction in transgenic Caenorhabditis elegans. A 44-year-old male patient with severe L4 and L5 spinal ste-nosis underwent CEI for low-back pain and sciatica. The results showed that between fungicide treatments and control, the spatial niche breadth of Rhizoctonia solani was different, while its temporal niche breadth was similar. This theoretical paper reviews the growing corpus of interactional research on ASD, including discourse analysis (DA) and conversation analysis (CA) approaches.

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Involvement of cAMP and beta-adrenoceptors in the relaxing effect elicited by flavonoids on rat uterine smooth muscle. Transgenic mice with increased hexosamine flux specifically targeted to beta-cells exhibit hyperinsulinemia and peripheral insulin resistance. Sixteen idiopathic oligospermic or azoospermic men entered the study. Moreover, p53 was unable to regulate the transcription of bax promoter fragments up to 6.5 kb in length. The findings obtained in this large and unselected data set confirm patterns previously reported in smaller and quite selective samples, most of them obtained in the United States.

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To what extent there is overlap in terms of brain regions and specific neurons for each circuit is being actively investigated. As carriers, there is no limitation in the size of foreign antigens that can be inserted in the membrane and the capacity of all spaces including the membranes, peri-plasma and internal lumen of the ghosts can be fully utilized.

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These results suggest that more than half of the genes induced by cagPAI-positive H pylori depend on NF-kappaB and ERK signaling activation, and these pathways may play a role in the gene expression induced by host-bacterial interaction which may associate with H pylori-related gastro-duodenal diseases. Cognitive appraisal accuracy moderates the relationship between injury severity and psychosocial outcomes in traumatic brain injury.

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At this time, interest in developing inhibitors is limited to viruses that cause chronic disease, viruses that have the potential to cause large-scale epidemics, or viruses that are sufficiently ubiquitous that treating an acute infection would be beneficial even if the infection was ultimately self-limiting. Spontaneous locking of the knee after anterior cruciate ligament reconstruction as a result of a broken tibial fixation device.

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Chemical functionalization can significantly modify their properties which, in addition to improving their processibility, when mixed in polymers can enhance the overall mechanical and electrical properties of the composites. It was demonstrated that macrophages ingest selectively or preferentially aggregated oxidized LDL, but not native size oxidized LDL. Seventy percent of the prospective group of 30 patients had pain during the first postoperative week, and only 1 patient had pain persisting for more than 2 months.

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Acarviostatin III03 is the most potent alpha-amylase inhibitor known to date. Diverse lines of evidence, including genetic and pharmacological data obtained in rodents and humans, support a role for the melanocortin MC(3) and MC(4) receptors in the regulation of energy homeostasis. Complementary information obtained from the two methods has revealed plenty of structural information and led to the fast on-line structure determination of N1 prior to its isolation and purification. In managing drug prices at the national level, orphan drugs represent a special case because the price of these agents is higher than that determined according to value-based principles. Because NOD mice were found to exhibit increased locomotion when placed for the first time in an open field, it is suggested that behavioral differences contribute to this differential effect of immobilization upon circulating glucose levels in NOD and C57BL/6 mice.

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Destructive osteoblastoma of the cervical spine with complete neurologic recovery. The patients received monthly obstetric and neurologic examinations, and the blood levels of AEDs were tested monthly. We used genetic, physiological and cell biological approaches to show that reorganisation of the actin cytoskeleton is required for dark-induced stomatal closure.

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Down-regulation of soluble fms-like tyrosine kinase 1 expression in invasive placentation. Thirty-six patients had ductography for the investigation of blood-stained or serous nipple discharge.

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Moreover, FGF9 stimulated OPN expression irrespective of the differentiation stage of the cells or culture conditions. 1h Post-load Blood Glucose in the Identification of Proatherogenic Cardiometabolic Profile in Obesity.

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These findings may have important implications in the development of PM02734 because tumor cells with high FA2H expression are expected to be particularly sensitive to this drug. Circular dichroism and fluorescence spectroscopy, together with dynamic light scattering measurements and dye-aggregate complexation, provided additional insights into the distinctions between aggregated and native LY307161. The authors performed a secondary analysis of the National Treatment Improvement Evaluation Study (NTIES), a prospective cohort study conducted during 1993 to 1995. Bacteriophages enhance bacterial survival, facilitate bacterial adaptation to new environmental conditions, assist in the adaptation to a new host species, and enhance bacterial evasion or inactivation of host defense mechanisms. Molecular hydrogen adsorbed on benzene: Insights from a quantum Monte Carlo study.

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Glucose, leucine, succinic acid methyl ester, and alpha-ketoisocaproic acid all markedly stimulate insulin release but do not increase glutamate levels in pancreatic islets. The older patients are and the later ADHD is attended, the more problems they have. Lithium augmentation in the continuation phase of treatment of unipolar major depressive disorder effectively protects patients against a relapse. A physiologic 3-point loading model was used to measure dorsal displacement of the navicular on the talus with 1 or 2 cannulated 4.5-mm screws across the talonavicular joint both with and without one 7.3-mm cannulated screw across the subtalar joint. We utilized a site-specific cross-linking technique to investigate the mechanism of nucleosome remodeling by hSWI/SNF.

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This paper reviews the applications of HRMS for the analysis of NPS in forensic drug chemistry and analytical toxicology. The definition of the Na/K pump currents was the ouabain-sensitive currents, where ouabain is a specific Na/K ATPase inhibitor. In a test with three mutagens, one potent (ethylnitrosourea) and two weak (1,2-dimethylhydrazine and methyl methanesulphonate), ten weekly treatments induced ten times the frequency of Dlb-1 mutations induced by a single treatment in each case, a result that is consistent with perfect additivity. Oligonucleotide degradation studies were carried out in fetal calf serum. Guidelines and techniques for the generation of induced pluripotent stem cells.

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Eyelid movements occurring during spontaneous blinks were recorded bilaterally using a modification of the electromagnetic search coil technique. Prognostic significance of tissue DF3 antigen and CA15-3 tumor marker in primary breast cancer. Although all anatomic targeting methods provide accurate STN localization, a combination of the three methods offers the best correlation with the final physiological target.

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Leucocytes, isolated from naive, naturally-infected fish and carp injected intraperitoneally with cestode extracts, were exposed to parasite extracts (protein concentrations 0-10.0 microg ml-1), for up to 24 h in the presence or absence of carp serum. Dendritic development of dentate granule cells in the absence of their specific extrinsic afferents.

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Replacement of Biphenyl by Bipyridine Enabling Powerful Hole Transport Materials for Efficient Perovskite Solar Cells. The purpose of this study was to examine whether an early sleep session following action observation has benefit over action observation alone in the rehabilitation of older adults after stroke. Clinical and radiological evaluation of long-term results of stereotactic proton beam radiosurgery in patients with cerebral arteriovenous malformations. Preliminary studies showed that phenyllactic and 4-hydroxy-phenyllactic acids were also contained in the bacterial culture filtrate of strain 20B.

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A synovial stimulating protein (SSP) has previously been isolated from rheumatoid arthritis synovial fluid and from the culture fluid of rheumatoid arthritis synovial fibroblasts. The macroporous calcium phosphate bioceramics with pore diameters of 300 microm to 600 microm were developed using a porogen burnout technique, and the chitosan sponges were formed inside the pores of the bioceramics by first introducing chiosan solution into the pores followed by a freeze-drying process. We have developed a high-throughput approach for assessment of DNA copy-number changes, through use of high-density synthetic oligonucleotide arrays containing 116,204 single-nucleotide polymorphisms, spaced at an average distance of 23.6 kb across the genome. In other studies CBF was measured during increases in systemic arterial pressure, before and after denervation of arterial baroreceptors.

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We describe a case of a bladder neck fistula in a 25-year-old lady presenting with true urinary incontinence, vaginal constriction and induration, with vaginal length reduced to only 1.5 cm. Lactic dehydrogenase, aldolase and glutamic-oxalacetic and glutamic-pyruvic transaminases The nuclei had delicate nuclear membranes, with finely dispersed chromatin and occasional micronucleoli. The dose of irradiation ranged from 2000 to 3000 rad over 25-44 days.

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We found that MKP-1 overexpression stimulates PARP-1 and poly(ADP-ribose) (PAR) protein expression and cisplatin resistance while its downregulation suppresses PARP-1 and PAR protein expression and cisplatin resistance. In biliary atresia mechanisms of progressive liver injury leading to need of liver transplantation after successful portoenterostomy remain unknown.

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Polarized fluorescence and absorption of macroscopically aligned Light Harvesting Complex II. Neuropsychological tests with lateralizing value in patients with temporal lobe epilepsy: reconsidering material-specific theory. 8 alpha-Estra-1,3,5(10)-triene-1,3, 17 beta-triol as a special type of estrogen having a high vaginotrophic activity and a low uterotrophic activity in castrated mice.

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Revisiting the debate of voluntary versus mandatory HIV/AIDS testing in U.S. The developmental requirements for immunological memory, a central feature of adaptive immune responses, is largely obscure. Alternative models have been considered where the variance associated with the discrete amplitudes is sufficiently large apo ronar vs g-claron 355mm such that no quantal amplitudes can be detected. Molecular cloning of Brugia malayi antigens for diagnosis of lymphatic filariasis.

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A retrospective review of their medical records and radiology was undertaken. Overexpression of miR-98 repressed the proliferation of HSFBs by targeting Col1A1. Atrial fibrillation occurs frequently in patients with congestive heart failure and commonly results in clinical deterioration and hospitalization. Therefore, the methods used for the analysis of the sanitary water quality must allow the recovery of the physiological injured cells. A significant reduction in CVD risk can be achieved if SFAs are replaced supralip max dose ibuprofen by unsaturated fats, especially polyunsaturated fatty acids.