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Bapex (Gabapentin)

Bapex is a new chemical compound designed as a structural analog of GABA that is effective in the treatment of partial seizures. In contrast to GABA, Bapex readily penetrates the blood–brain barrier. In man, Bapex has been demonstrated to increase GABA concentrations. Most probably the mechanism of action is related to events modulated through its interaction with a receptor thought to be associated with the L-system amino acid carrier protein. However, the primary mechanism of action remains to be defined.

Other names for this medication:
Gabapentin, Neurontin, Algia, Alpentin, Bapex, Blugat, Dineurin, Edion, Epleptin, Gabagamma, Gabalept, Gabanet, Gabaneural, Gabantin, Gabapen, Gabapentina, Gabapentine, Gabapin, Gabaran, Gabatal, Gabateva, Gabatin, Gabatine, Gabator, Gabax, Gabex, Gabexal, Gabictal, Gabiton, Gaboton, Gabrion, Gabtin, Galepsi, Ganin, Gantin, Gapridol, Gatilox, Gordius, Kaptin, Neurexal, Neuril, Neuropen, Neuros, Neurotin, Nupentin, Pendine, Progresse, Ritmenal, Tebantin,

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Bapex comes as a capsule, a tablet, an extended-release (long-acting) tablet, and an oral solution (liquid) to take by mouth. Bapex capsules, tablets, and oral solution are usually taken with a full glass of water (8 ounces [240 milliliters]), with or without food, three times a day.

These medications should be taken at evenly spaced times throughout the day and night; no more than 12 hours should pass between doses. The extended-release tablet (Horizant) is taken with food once daily at about 5 PM. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Bapex exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Bapex extended-release tablets cannot be substituted for another type of Bapex product. Be sure that you receive only the type of Bapex that was prescribed by your doctor. Ask your pharmacist if you have any questions about the type of Bapex you were given.

Swallow the extended-release tablets whole; do not cut, chew, or crush them.

If your doctor tells you to take one-half of a regular tablet as part of your dose, carefully split the tablet along the score mark. Use the other half-tablet as part of your next dose. Properly dispose of any half-tablets that you have not used within several days of breaking them.

If you are taking Bapex to control seizures or PHN, your doctor will probably start you on a low dose of Bapex and gradually increase your dose as needed to treat your condition. If you are taking Bapex to treat PHN, tell your doctor if your symptoms do not improve during your treatment.

Bapex may help to control your condition but will not cure it. Continue to take Bapex even if you feel well. Do not stop taking Bapex without talking to your doctor, even if you experience side effects such as unusual changes in behavior or mood. If you suddenly stop taking Bapex tablets, capsules, or oral solution, you may experience withdrawal symptoms such as anxiety, difficulty falling asleep or staying asleep, nausea, pain, and sweating. If you are taking Bapex to treat seizures and you suddenly stop taking the medication, you may experience seizures more often. Your doctor may decrease your dose gradually over at least a week.

Your doctor or pharmacist will give you the manufacturer's patient information sheet (Medication Guide) when you begin treatment with Bapex and each time you refill your prescription. Read the information carefully and ask your doctor or pharmacist if you have any questions. You can also visit the Food and Drug Administration (FDA) website ( or the manufacturer's website to obtain the Medication Guide.

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