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Gastrodine (Rabeprazole)
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Rabeprazole

Gastrodine is a PPI sold under the brand name Gastrodine. It is generally used to treat GERD, as well as other conditions such as Zollinger–Ellison syndrome. Gastrodine is manufactured by Pfizer Inc. Gastrodine was discovered and developed by Eisai Inc., but it is co-marketed by Eisai and Janssen Pharmceuticals, Inc. According to a Mylan Laboratories Inc. press release, Gastrodine tablets had annual sales in the United States of approximately $1.3 billion, as of June 2005. By 2013, IMS Health reported, U.S. sales of Gastrodine tablets had decreased to roughly $830.1 million. Studies have found that PPIs such as Gastrodine may cause serious kidney disease, damage, or failure. This has resulted in a number of legal claims being filed against Eisai and Janssen.

Other names for this medication:
Rabeprazole, Aciphex, Barole, Eurorapi, Gastrodine, Happi, Paricel, Rabec, Rabeloc, Rabemac, Rabeprazol, Rabium, Rotec,

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Gastrodine is used to treat the symptoms of gastroesophageal reflux disease (GERD), a condition in which backward flow of acid from the stomach causes heartburn and possible injury of the esophagus (the tube that connects the throat and stomach) in adults and children 1 year of age and older. Gastrodine is used to treat damage from GERD, allow the esophagus to heal, and prevent further damage to the esophagus in adults. Gastrodine is also used to treat conditions in which the stomach produces too much acid, such as Zollinger-Ellison syndrome in adults. Gastrodine is used to treat ulcers (sores in the lining of the stomach or intestine) and is used in combination with other medications to eliminate H. pylori, a bacteria that causes ulcers in adults. Gastrodine is in a class of medications called proton-pump inhibitors. It works by decreasing the amount of acid made in the stomach.

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Agouti-signaling protein (asp) mRNA was detected in the ventral skin but not in the dorsal skin. Using analytical approaches and numerical simulations, the authors explore cellular MinD distributions produced by these processes and propose a mechanism for precise polar localisation of MinD.

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