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Acyl (Acyclovir)

Acyl is an antiviral drug, a synthetic nucleoside analogue, that has inhibitory activity (interferes with viral replication) against the herpes viruses, including herpes simplex 1 and 2 (cold sores and genital herpes), varicella-zoster (shingles and chickenpox), and Epstein-Barr virus (mononucleosis). Viruses take over living cells and reproduce themselves, often at the expense of the host cell. The Acyl is converted to an active form by the virus itself, and the virus then uses the active form of Acyl rather than the nucleoside it normally uses to manufacture DNA, a critical component of viral replication. Incorporation of active Acyl into new viral DNA stops the production of the DNA. Virally infected cells absorb more Acyl than normal cells and convert more of it to the active form, which prolongs its antiviral activity. The FDA approved Acyl in March 1982.

Other names for this medication:
Acyclovir, Abduce, Acic, Aciclobeta, Aciclomed, Aciclostad, Aciclovirum, Acifar, Acihexal, Aciklovir, Acitop, Acivir, Acivirex, Acivision, Acix, Actios, Activir, Acycloguanosine, Acyl, Acyrax, Acyvir, Aklovir, Antivir, Asiviral, Avir, Aviral, Avix, Avorax, Blistex, Cicloferon, Cicloviral, Clinovir, Clirbest, Clopes, Clovate, Clovir, Cusiviral, Cyclomed, Cyclovax, Cyclovex, Cyclovir, Danovir, Declovir, Epsin, Eurovir, Hascovir, Hernovir, Herperax, Herpesil, Herpesin, Herpex, Herpin, Herplex, Heviran, Immunovir, Lisovyr, Lovir, Lovire, Lovrak, Medovir, Menova, Ocuvir, Poviral, Ranvir, Remex, Rexan, Scanovir, Sitavig, Sophivir, Soviclor, Supraviran, Telviran, Uniplex, Vilerm, Viraban, Viralex, Viratac, Viratop, Virest, Virestat, Virex, Virless, Viroclear, Virolex, Viromed, Virosil, Virostatic, Virovir, Virucid, Viruderm, Virustat, Virux, Vivorax, Xiclovir, Xorox, Zevin, Ziverone, Zoral, Zorax, Zoraxin, Zovirax,

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Sesaren, Antara, Alapren, Anamet, Ziverone, Valto, Rokso, Zaroxolyn, Omnic, Alltop, Rafen, Lanproton, Novofen, Normax, Nitrest, Flazol, Novamox, Sitran, Sortiva, Otrivine, Vensir, Cofac, Staxyn, Parkopan, Ramoclav, Hexarone, Hydrochlorothiazide, Pfeil, Bapex, Prestarium, Himox, Bioclavid, Ultrazac, Tulip, Trova, Venla, Trizol, Zimaquin, Rhewlin, Ibudolor, Parlodel, Klarithran, Pantac, Forcid,

Topical Acyl comes as a cream and an ointment to apply to the skin. Acyl cream is usually applied five times a day for 4 days. Acyl cream may be applied at any time during a cold sore outbreak, but it works best when it is applied at the very beginning of a cold sore outbreak, when there is tingling, redness, itching, or a bump but the cold sore has not yet formed. Acyl ointment is usually applied six times a day (usually 3 hours apart) for 7 days. It is best to begin using Acyl ointment as soon as possible after you experience the first symptoms of infection. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use topical Acyl exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor.

Your symptoms should improve during your treatment with topical Acyl. If your symptoms do not improve or if they get worse, call your doctor.

Acyl cream and ointment are for use only on the skin. Do not let Acyl cream or ointment get into your eyes, or inside your mouth or nose, and do not swallow the medication.

Acyl cream should only be applied to skin where a cold sore has formed or seems likely to form. Do not apply Acyl cream to any unaffected skin, or to genital herpes sores.

Do not apply other skin medications or other types of skin products such as cosmetics, sun screen, or lip balm to the cold sore area while using Acyl cream unless your doctor tells you that you should.

To use Acyl cream, follow these steps:

  1. Wash your hands.
  2. Clean and dry the area of skin where you will be applying the cream.
  3. Apply a layer of cream to cover the skin where the cold sore has formed or seems likely to form.
  4. Rub the cream into the skin until it disappears.
  5. Leave the skin where you applied the medication uncovered. Do not apply a bandage or dressing unless your doctor tells you that you should.
  6. Wash your hands with soap and water to remove any cream left on your hands.
  7. Be careful not to wash the cream off of your skin. Do not bathe, shower, or swim right after applying Acyl cream.
  8. Avoid irritation of the cold sore area while using Acyl cream.

To use Acyl ointment, follow these steps:

  1. Put on a clean finger cot or rubber glove.
  2. Apply enough ointment to cover all of your sores.
  3. Take off the finger cot or rubber glove and dispose of it safely, so that it is out of reach of children.
  4. Keep the affected area(s) clean and dry, and avoid wearing tight-fitting clothing over the affected area.

Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient. Read this information before you start using Acyl and each time you refill your prescription.

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Furthermore, each repeat is predicted to have the secondary structure of a beta-grasp superfold motif, a motif not found in other MAPs. Cardiac sympathetic and parasympathetic tones were determined after methylatropine and propranolol treatments.

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A case of solitary plasmacytoma of the lung in a 14-year-old boy is reported. The stimuli were unambiguous real 3-D equivalents of the computer-generated stimuli we used in a previous experiment.

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Peak oxygen uptake is not determined by cardiac noradrenaline spillover in heart failure. Ultrastructural changes in the intestinal mucosa in rats in the terminal stage of acute uremia. Co-localization of GABA with nicotinamide adenine dinucleotide phosphate-dependent diaphorase in neurones in the dorsolateral periaqueductal grey matter of the rat.

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Levels of prostaglandin E2 and leukotriene B4 in tears of vernal conjunctivitis patients during a therapeutic trial with indomethacin. A histochemical study of DPN-diaphorase in human white matter with some notes on myelination. Several studies have shown that apoptotic pathways control fragmentation of unfertilized ovulated oocyte, induced by doxorubicin.

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Polycythemia vera and essential thrombocythemia pose specific management issues that distinguish them from other chronic myeloproliferative disorders. A brief description of Chaos theory is given and three microbiological areas of unpredictability are discussed: uncertain identity of isolates, unknown stress damage, unexplored variation of individual colony populations. Here, we further investigate cellular control of circuit rewiring through the analysis of mutants obtained in a forward genetic screen. This study indicates that during development of cirrhosis, there is reciprocal transfer of retinoid metabolites between the circulation and the liver.

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To investigate circulating thrombopoietin (TPO) concentrations in systemic sclerosis (SSc). If she prolongs her use to 20 years, the gain of life expectancy and disease-free life expectancy is doubled.

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Compared with the tricortical bone graft, both cages showed significantly better distractive properties. This motif mediates HEF1 homodimerization and HEF1 heterodimerization with a recognition specificity similar to that of the transcriptional regulatory HLH proteins Id2, E12, and E47. gingivalis and the presence of periodontal disease are independently related to high CRP levels. However, each methodology has different property due to its assumption and algorithms.

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The average period of blood sampling after transfusions was 5.3 days. Several genetic models were used ranging from near dominant to fully recessive. The infective risk in Italy today: the role of the domestic environment The steady-state levels of Cdk2, Cdk4 and Cyclin A proteins were unaffected by HPR, while those of Cyclin D1 were significantly reduced in all three cell lines. Increasing antimicrobial resistance in bacteria is a major health problem and requires the implementation of stringent policies to optimize the use of antibiotics.

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We proposed to identify the long-term effectiveness of such a procedure. A study was made of all cases of transitional cell cancer of the anus or rectum in the records of the University of California Medical Center, San Francisco. Six urinary VOCs were isolated from patients with iMN using GC/MS. DMPA and implants have played an important role in the attempt to prevent teenage pregnancies. Zerumbone modulates CD1d expression and lipid antigen presentation pathway in breast cancer cells.

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The effect of left and right poses on the expression of facial emotion. On the contrary, the autoantibodies enhanced polymerization in prothrombin time assays, and accelerated it in tissue thromboplastin inhibition tests, with no effect on fibrinolysis.

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acyl protein thioesterase enzyme

The methodological improvement included the modification of the size density function based on a realistic assumption of particle size distributions, the application of a new and comprehensive curvilinear collision model, and special adjustment for the mass transfer of a doublet of particles that were very different in size. Plasma samples obtained from cancer patients before surgery showed C3 activation capacities corresponding to those of samples from patients with benign disease. Two patients with painful lytic lesions of the vertebral pedicle were treated with percutaneous pediculoplasty. The peptide alpha-helix cannot match its hydrophobic face to the rigid planar graphite surface without partially unfolding. Most differences in joint motions between two groups were found at the hip and knee either in LHS or HHS condition.

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Other recurrent changes included loss of chromosomes 4q and 6q, regions shown to contain one or more tumour suppressor genes. Choledochoduodenostomy as internal drainage of the common bile duct and blind suturing in inflammatory diseases of the bile ducts Traditional healers as tuberculosis treatment supervisors: precedent and potential. A caspase-independent pathway of MHC class II antigen-mediated apoptosis of human B lymphocytes.

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The aim of this study was to investigate modulation of T cell immunity for the treatment of experimental arthritis, via enhanced expression of SOCS-3 in splenic antigen-presenting cells (APCs) obtained after intravenous injection of adenovirus encoding SOCS-3. The VPS is delivered through the sheath, which is sectioned and removed. These results indicate that proliferation of BaF3 cells requires signals induced by the proximal as well as the distal region of the beta subunit of the GM-CSF receptor, and that serum alleviates the requirement of signals induced by the distal region.

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The versatility of negative pressure wound therapy with reticulated open cell foam for soft tissue management after severe musculoskeletal trauma. To determine whether estrogen sensitivity is ancestral or a unique characteristic of vertebrate ERs, we isolated and characterized ERs from two annelids, Platynereis dumerilii and Capitella capitata, because annelids are the sister phylum to mollusks and have been shown to produce and respond to estrogens. Analysis of secondary pauses following termination of rapid atrial pacing in man.

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Identifying the risk factors causing slip-induced falls is key to developing better preventive measures to reduce fall accidents. Blood urea nitrogen in the prediction of in-hospital mortality of patients with acute aortic dissection. Analysis of the cases of malignant neoplasms registered at the Centro Oncologico di Crema in the years 1951-1960 Laparoscopic-facilitated sigmoid resection is a feasible intervention for all forms of complicated diverticular disease and yields marked reductions in operating time, conversion rate, and operative and general costs. 182min, respectively), and both predicted rebound elevation of LVEDP after abrupt NTG withdrawal.

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Drawing on the intellectual resources of a Hegelian-inflected historical materialism and realism, we challenge both claims by arguing for a post-race, post-ethnicity sociology of group formation, one which allows a greater scope for agency in the determination of social life. Remyelination of areas of ethidium bromide-induced demyelination in the caudal cerebellar peduncle reached completion by 4 weeks in young adult rats (2 months) but was not complete until 9 weeks in old adult rats (9-12 months). Utilization of embryo development technique of Brachydanio rerio to evaluating toxicity on various chemicals The methods developed are in good agreement with the experimental data.

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tuberculosis was eventually controlled at an approximately stationary level in the lungs, livers, spleens and kidneys of BALB/c mice, and in all of these organs except the lungs in DBA/2 mice. It is predicted that the OAuNN(-) anion is a linear singlet molecule and the AuNO(-) anion is a bent doublet molecule. As expected, Sec14pK66,239A fails to meet established criteria for a PITP in vitro and fails to stimulate phosphoinositide production in vivo. Huntington disease (HD) is a fatal neurodegenerative disorder involving reduced muscle coordination, mental and behavioral changes, and testicular degeneration. Airway complications of relapsing polychondritis (RP), including tracheobronchial stenosis, can be fatal.

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This strain was sensitive to the presence of caffeine, Calcofluor white and Congo red, all drugs known to affect mutants defective in the signal transduction pathway ensuring cellular integrity in which Pkc1p is a central component. Our data also indicated that the gradual unbinding of the chaperone from the PapA groove has increasingly strong structural consequences.

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Effects of radiation on one of two Yoshida sarcomas transplanted into the same animal. These compounds may account for the use of Anisomeles indica in folk medicine to treat inflammation.

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Angiotensinogen and angiotensin-converting enzyme genotypes, and day and night blood pressures in elderly Japanese hypertensives. Massive hemothorax after removal of subclavian vein catheter: a very unusual complication. Platelets prepared by standard techniques contain significant numbers of donor leukocytes, which are responsible for several adverse effects. In summary, combining GWASs and regulatory elements through machine learning could provide additional information for understanding the mechanism of osteoporosis. Effect of D-glucose on induction of xylose reductase and xylitol dehydrogenase in Candida tropicalis in the presence of NaCl.

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Using the clearance method in children with obstructive pyelonephritis were investigated the changes of the renal excretory and ion-regulating functions before and after the operation. To investigate the effect of different levels of F(IO2) on the accuracy of V(O2), V(CO2), and respiratory quotient (RQ), measurements were performed at F(IO2) target values of 0.25, 0.40, and 0.60. Treatment of KKAy mice with pioglitazone, an anti-diabetic thiazolidinedione, partially restores insulin-dependent changes in PI 3-kinase. However, there was no such association in women with higher levels of knowledge.

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Arterial line placement in the radial, humeral, axillary or femoral are also described as well as the aid of ultrasonography for peripheral insertion of central catheters (PICC Lines). Rituximab, an anti-CD20 monoclonal antibody, is generally a safe and well-tolerated drug.

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Meanwhile, risk factors of health among students have been continuously worsening for the past dozen years or so. To clarify the cooperative role of VEGF and OPN in tumor angiogenesis, we stained VEGF, OPN, and CD34 immunohistochemically in 87 cases of stage I non-small cell lung cancer (adenocarcinoma, 55, and squamous cell carcinoma, 32). G3139 in combination with doxorubicin and docetaxel is well tolerated.

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Manifestation of the illness is connected with accumulation of several genetic determinants, while the clinical picture is additionally modified by environmental factors. Treatment with human TNF-alpha or addition of a neutralizing antibody against TNF-alpha receptor protein 80 to mouse TNF-alpha resulted in attenuated induction of apoptosis, suggesting that coengagement of the two TNF-alpha receptor types is required for maximal impact. The aims of the study were to identify pathways from parent marijuana use to child problem behavior and parent-child relationships, and to evaluate whether effects of an earlier prevention program delivered to parents when they themselves were early adolescents would have a protective effect on these relationships one generation later. By immunohistochemistry, the expression of OG-4 antigen was observed on human GC and large luteal cells, but not on thecal and small luteal cells.

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Preoperative barium enema examination was an unsatisfactory tool for detecting synchronous tumors. More than two-thirds of the esophagus was involved in three patients and four had a recurrence in an esophagogastric anastomosis. Prospective, nonrandomized, comparative (self-controlled) trial.

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The isotonic osmolality ratio was selected as optimum stock isotonic Percoll solution(SIP). Since the regions where these structures appeared exhibited neuronal loss with gliosis, these data suggest that a cytoskeletal abnormality involving tau protein in glia might be associated with the degenerative process of MND-D.

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Genetically defined rats learned a complex maze in noise of moderate intensity (70 dB) or in quiet. We hypothesize that PM induces endothelial cell (EC) cytoskeleton rearrangement via Rho GTPase-dependent pathways to facilitate vascular hyperpermeability.

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Iron status and colorectal cancer in symptomatic elderly patients. Serum concentrations of IgG anti-dsDNA antibodies were not significantly modified. Construct validity of the Sivik Psychosomaticism Test and test of operational style: correlations with four Minnesota Multiphasic Personality Inventory (MMPI) subscales. To describe a new fixation and embedding method for tissue samples, immunohistowax processing, which preserves both morphology and antigen immunoreactivity, and to use this technique to investigate the role of dendritic cells in the immune response in peripheral tissues.

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We examined the prevalence of HIV-associated cutaneous disorders as well as the frequency and efficiency of UV-radiation in HIV-infected patients by evaluating the clinical records of 1310 patients seen between and 1994 and 1996. The role of surgery in the therapeutic balance of locally advanced rectal neoplasms needs to be redefined in the light of recent reports on the efficacy of radio- and chemotherapy in neoadjuvant treatment. subtilis cell walls are stabilized in the WB700 strain as well as in the sigD mutant. We measured the levels of resistance, the expression profiles of hemolymph proteins, the phenoloxidase (PO) activity, and the differential number of circulating hemocytes in resistant and susceptible individuals.

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acyl substitution alcohol withdrawal 2016-07-19

In anaesthetized rats the lumbosacral spinal cord was exposed by laminectomy and the pre-emptive effect of peg interferon alfa and ribavirin package intrathecal AP-5 upon the hyper-reflexia associated with chemical inflammation of the bladder was investigated. Soluble interleukin-2 receptor as a marker for progression of coronary artery calcification in type 1 diabetes.

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BGN can inhibit phosphorylation of IkappaB, restrain the activity of NF-kappaB and change the binding level of NF-kappaB with DNA. This process may result in the accumulation of pleiotropic fitness costs associated with host resistance, and could breakdown avistar airport parking houston hobby coupon coexistence. Effect of intranasal histamine challenge on Eustachian tube function. Emergency surgical resection was performed for tissue diagnosis and spinal decompression. The phenicol/lincosamide/oxazolidinone/pleuromutilin/streptogramin A multidrug resistance gene cfr was detected in isolates of both clonal lineages, rendering a spread to humans with exposure to swine farming possible.

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We studied synthetic modifications of N-mercaptoacylamino acid derivatives to develop a new class of leukotriene A(4) trum hand cycles for sale (LTA(4)) hydrolase inhibitors. This algorithm is an effective tool to improve emergency room treatment. The knowledge of these rare anomalies is important for the difficult diagnosis, an effective surgical therapy, and to avoide diagnostical misconstructions.

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Thyroid ultrasonography in patients with a previous episode of amiodarone induced thyrotoxicosis. We also determine how cytotoxicity is affected by the variability in duration of cell cycle phases and by cell cycle length in the presence or zitrotek 1000 mg fiyat ikinci absence of entrainment by the circadian clock. Clinicians should be mindful of the risk of hyperkalemia when prescribing RAAS inhibitors to patients with heart failure. Cholinergic modulation of spontaneous activity in rat dorsal cochlear nucleus. The current study focused on the influence of environmental factors (e.g., pH value of the culture, oxidation-reduction condition, light, and cultured age of bacteria on the reduction of mercury(II) to elemental mercury (Hg0) that occurred on the surfaces of suspended particulate matter.

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From our duomox uk athletics database, we identified 4 patients who received DOA after CAD and 4 patients after CVT. Multiple regression techniques were used to determine the independent association of initial cerebrovascular risk factors with depressive symptoms and diagnoses at 1 year.

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A string of oocytes from Bufo arenarum (Ba) was inseminated with spermatozoa from Ba, Leptodactylus chaquensis (Lch), or Bufo paracnemis (Bp). Clinical evaluation of heparin-coated circuits for trazodone 50 mg sleep aid 2015 routine coronary artery bypass grafting surgery: a prospective randomized study. Both adults and children demonstrated a significant informational masking effect, with children showing a larger effect on average.

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Ozone sensitivity of currant tomato (Lycopersicon pimpinellifolium), a potential bioindicator species. Around 3 weeks after initial presentation, he developed massive repaglinide medication gastrointestinal haemorrhage requiring resuscitation and emergency laparotomy.

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Six endocannabinoids were measured in serum of the patients enrolled. Arachidonic acid induced platelets citalopram overdose toxbase to produce large amounts of malondialdehyde.

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Postoperative death caused by internal suffocation of alimentary origin Patients with DSM-III-R panic disorder were recruited by screening consecutive primary care tramadol 25mg dosage clinic attenders and then administering a structured diagnostic interview for panic disorder.

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Inhibitory effect of supramolecular polyrotaxane-dipeptide conjugates on digested peptide uptake via intestinal human peptide transporter. Consistent with prior research, skilled readers obtained more preview benefit from the homophone preview than from the orthographic preview. Various mutant proteins were created and their DNA-binding specificity was determined by gel shift what does generic losartan look like assay. Preparing is about unleashing the strengths of each person on the crew.

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Concurrent single-agent chemotherapy trials, hypoxic cell sensitizer trials, and multiagent chemotherapy trials are presented. The treated cells showed exchange of nuclear proteins from extracts such as incorporation of Xenopus-specific histone B4 and Lamin LIII into nuclei. Their high phenol, lipid and organic acid concentrations turn them into what does a losartan 100 mg pill look like phytotoxic materials, but these wastes also contain valuable resources such as a large proportion of organic matter and a wide range of nutrients that could be recycled. Application of advanced techniques for the assessment of bio-stability of biowaste-derived residues: A minireview.