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Asquam (Ketoconazole)
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Ketoconazole

Asquam is the world’s first oral azole antifungal. First launched by Janssen Pharmaceutica (Belgium) in 1985, it transformed the treatment of oral and oesophageal candidiasis and some endemic mycoses such as coccidioidomycosis. This week, the FDA restricted its use to the occasional patient with endemic mycoses, as a last resort. The FDA cites “severe liver injuries and adrenal gland problems, and advising that it can lead to harmful drug interactions with other medications”, as the reason for it shift in position. Early after launch, Asquam was extensively used for skin fungal infections, and was very effective for many and convenient. Unfortunately about 1 in 10,000-15,000 developed severe hepatic reactions, which were either fatal, or more recently required transplantation. Adrenal dysfunction is also a significant issue. Asquam tablets are used throughout the world, as it is less expensive than other antifungals, but its use should be curtailed for all but the shortest courses. Fluconazole is a much safer alternative. Asquam (Asquam) shampoo carries no risk.

Other names for this medication:
Ketoconazole, Nizoral, Akorazol, Arcolan, Arcolane, Asquam, Biogel, Clarazole, Conazol, Daktagold, Daktarin, Dezor, Diazon, Dikoven, Eumicel, Extina, Funginoc, Fungoral, Ilgem, Kenazol, Kenazole, Ketazol, Ketokonazol, Ketolef, Ketovid, Ketozal, Liondox, Lizovag, Micoral, Micosin, Muzoral, Mycoderm, Noell, Orifungal, Oronazol, Panfungol, Perative, Phytoral, Pristinex, Tiniazol, Tinuvin, Xolegel, Yucomy, Zoloral,

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Asquam is used to treat skin infections such as athlete's foot, jock itch, ringworm, and certain kinds of dandruff. This medication is also used to treat a skin condition known as pityriasis (tinea versicolor), a fungal infection that causes a lightening or darkening of the skin of the neck, chest, arms, or legs. Asquam is an azole antifungal that works by preventing the growth of fungus.

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Some effects of a low sodium diet high in potassium on the renin-angiotensin system and plasma electrolyte concentrations in normal dogs. In the present work, it was found to inhibit cell growth and confer chemosensitivity to cisplatin in two lines of human melanoma cells, poorly responsive to cisplatin. Combination therapy may be superior to monotherapy in severely ill patients with Gram-negative bacteremia.

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Inflammatory pseudotumor of the liver in a patient with chronic hepatitis C: difficulty in differentiating it from hepatocellular carcinoma. Endocervical cytobrush for the detection of cervical dysplasia before large loop excision of the transformation zone (LLETZ). This method seems to be appropriate to demonstrate a delayed atrial conduction that might be a possible risk factor of reinitiation of AF. Rats were rendered leukopenic by injection of an antibody against leukocytes, and the mesentery was superfused with CMP 48/80 during intravital microscopy. To review the literature on high-frequency jet ventilation in European and North American institutions, we performed a search in a computerized database (MEDLINE) covering the period from 1990 until the present time, describing the use of high-frequency jet ventilation in over 7000 patients.

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Molecular biology in orthopaedics: the advent of molecular orthopaedics. Under the circumstances normally encountered during casework analysis, PCR contamination was never noted.

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Vocal fold biology research is emerging as a vital area of study in laryngology. Differential effects of training intertrial interval on acquisition of trace and long-delay fear conditioning in rats. We directly investigated a neural correlate of perceptual learning in the primary visual cortex using fMRI.

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The rat corticospinal tract was stimulated at the medullary pyramid, and field potentials were recorded at the cervical cord along an 200-microm interval lattice on the axial plane. The coevolving genotype showed a reduction in the growth rate, consistent with a cost of resistance, which may be responsible for a decline in its relative fitness.

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This work details changes to the UF-RIPSA software that include an expanded library of computational phantoms, attenuation coefficients for tabletop with pad, and calibration curves for the KAP meter. ATGs induce apoptosis and complement-mediated cell death in peripheral T-lymphocytes and have shown a reduction of leukocyte adhesion after ischemia-reperfusion (IRI). A Pilot Study on Professional Documentation: Do We Write From a Strengths Perspective? The procedure of choice for inguinal hernia repair has remained controversial for decades.

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Capacity strengthening through pre-migration tuberculosis screening programmes: IRHWG experiences. Statistic analysis of the data was performed using chi-square analysis and, when appropriate, a Fischer exact probability test. The major part of the noise reduction is achieved by an exchange of the originally installed light emitting diode by a laser diode placed outside the vacuum, where the light is coupled into the ultrahigh vacuum chamber via an optical fiber.

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Applying ANOVA to the variance in repeat number, we found a significant influence of repeat motif on microsatellite variability. Both groups had comparable demographic characteristics, as well as preoperative SF-12v2, ODI and VAS scores. Cell proliferation did not differ between groups after 1-5 days of culture. The GPs completed a questionnaire about their own patients while the data concerning the cardiac state of the patients were obtained from their problem lists. brucei comprises the basal body and nucleates the flagellum used for locomotion.

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What are the sexual boundaries between physiotherapists and their patients? Use of a new device, the MicroWick, to deliver medication to the inner ear. In the latter case, the few infected dendritic cells simultaneously presented an SAg and an antigen, i.e., peptide. On the colour of wing scales in butterflies: iridescence and preferred orientation of single gyroid photonic crystals.

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gamma-Glutamylcysteine ethyl ester for myocardial protection in dogs during ischemia and reperfusion. Recent decades have witnessed robust successes in conquering the acutely lethal manifestations of heart and vascular diseases. Moreover, calpain-cleaved Bcl-2 and Bid induced cytochrome c release from isolated mitochondria.

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These peri-articular masses developed around the shoulders in both patients, and the action of 1, alpha-hydroxycholecalciferol as a possible factor promoting this form of metastatic calcification is discussed. Leukocyte adhesion to vascular endothelium is related to inflammation and has been widely studied. Histopathological study of the meibomian glands in 72 autopsy cases Responses to treatment can differentiate chronic active liver disease with cholangitic features from the primary biliary cirrhosis syndrome. Contributions to the case material on ganglia of the internal ligament of the knee joint

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Dysphagia is a relatively common secondary complication in patients with traumatic cervical spinal cord injuries (TCSCI). Of 81 patients, 41 received antibiotics, of which 34 were treated for at least seven days. Before treatment prolactin values were elevated ranging from 27 to 125 ng/ml, while luteinizing hormone and progesterone levels failed to show ovulatory peaks or luteal phase progression. Only scattered cases with duplications and/or deletions in this region have been reported in the literature or in online databases.

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Anthocyanins are responsible for the different colors of ornamental plants. Tetrahydrobiopterin plays an essential role in nitric oxide synthase catalysis, not only as an allosteric modulator but also as a cofactor involved in electron flow through the enzyme. Design and characterization of anchoring amphiphilic peptides and their interactions with lipid vesicles. In the group of obese gravidae we found a significant higher rate of cases with induction of labor, protracted deliveries, breech presentation and operative deliveries.

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Ultrastructural studies of the mononuclear cells of peritoneal exudates induced by carrageenan indicated that those of newborn rats contained fewer lysosomes than adults. Unidirectional female-to-male IPV and bidirectional IPV are more associated with the characteristics of the female.

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Data on glycemic control provide sufficient evidence that self-management education is effective in community gathering places for adults with type 2 diabetes and in the home for adolescents with type 1 diabetes. The hypothesis was tested that psychosocial work stress, as defined by the model of effort-reward imbalance, mediates the effects of shift work on cardiovascular risk. The primary outcome was patient reported urinary incontinence on the EPIC (Expanded Prostate Cancer Index Composite) scale 6 and 12 weeks postoperatively. This is the first case of a late- presenting congenital diaphragmatic hernia reported in association with a previous ipsilateral lobectomy for congenital lobar emphysema.

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The 100-microm PTK ablation resulted in significantly more corneal scarring than the 15-microm PTK ablation. Respiratory tract inflammation during the induction of chronic bronchitis in rats: role of C-fibres. Repetitive intermittent duct obstruction in American opossums was achieved using an extraductal balloon occluder connected to a subcutaneous port system that was inflated three times for 24 hr within a five-day period. New conception prototypes have been recently described for ESBS.

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Rhodnius pallescens Barber 1932 is a silvatic species of Triatominae living sumatriptan mechanism of action in palm trees in Colombia and part of Central America. In this approach, the site of the nonunion is exposed medial to the flexor digitorum muscle and the proximal and distal ends of the site of the nonunion debrided up to healthy bleeding bone. Results of a positive control (17 beta-estradiol) study are presented to give an indication of the baseline associated with various test endpoints and to highlight the importance of nutrition in the experimental design.

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