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Lafigin (Lamotrigine)

Lafigin is an important anticonvulsant with activity against both focal and generalized onset seizures. It is also effective in the treatment of bipolar disorder and neuropathic pain. However, its use is associated with a significant incidence of adverse cutaneous reactions, mainly when concomitant therapy is administered. Rash is the most common adverse reaction of this antiepileptic agent and the most common reason for treatment discontinuation as it can be life-threatening. Children under polytherapy have a higher risk of this adverse event. Such cutaneous reactions range from mild rashes to more serious conditions such as Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis. SJS is thought to be a hypersensitivity reaction involving skin and mucous membranes.

Other names for this medication:
Lamotrigine, Lamictal, Daksol, Epitec, Flamus, Labileno, Lafigin, Lamal, Lambipol, Lamez, Lamictin, Lamidus, Lamirax, Lamitor, Lamitrin, Lamogine, Lamolep, Lamotrigin, Lamotrigina, Lamotrix, Lomarin, Meganox,

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Lafigin extended-release (long-acting) tablets are used with other medications to treat certain types of seizures in patients who have epilepsy. All types of Lafigin tablets (tablets, orally disintegrating tablets, and chewable tablets) other than the extended-release tablets are used alone or with other medications to treat seizures in people who have epilepsy or Lennox-Gastaut syndrome (a disorder that causes seizures and often causes developmental delays). All types of Lafigin tablets other than the extended-release tablets are also used to increase the time between episodes of depression, mania (frenzied or abnormally excited mood), and other abnormal moods in patients with bipolar I disorder (manic-depressive disorder; a disease that causes episodes of depression, episodes of mania, and other abnormal moods). Lafigin has not been shown to be effective when people experience the actual episodes of depression or mania, so other medications must be used to help people recover from these episodes. Lafigin is in a class of medications called anticonvulsants. It works by decreasing abnormal electrical activity in the brain.

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The hexokinase 2-dependent glucose signal transduction pathway of Saccharomyces cerevisiae. Induction of high-affinity GM-CSF receptors during all-trans retinoic acid treatment of acute promyelocytic leukemia. The Mississippi physician as an expert witness--must he accept token compensation? The data reports are concentrating on salmonellosis, tuberculosis, brucellosis and trichinellosis.

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Ileostomy should be the first choice of anastomotic leakage after laparoscopy-assisted right hemicolectomy and its efficacy is satisfactory. Vascular pattern and spectral parameters of power Doppler ultrasound as predictors of malignancy risk in thyroid nodules. An analytical expression based on four fitting parameters is proposed for a mathematical description of electron beam central axis depth dose distributions. This theory explains the co-occurrence of stereopsis and diplopia and how half-occlusions escape the suppression characteristic of binocular rivalry. Effect of rat intrinsic factor on vitamin B12 absorption in pernicious anemia.

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We report a novel role of Wnt signaling in organogenesis using the formation of the islet during pancreatic development as a model tissue. Of 36 plant species, only two species of ferns (Pityrogramma calomelanos and Pteris vittata), a herb (Mimosa pudica), and a shrub (Melastoma malabrathricum), seemed suitable for phytoremediation. Hospital admissions among patients with congestive heart failure (CHF) are a major contributor to health-care costs.

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Regenerated egg white/silk fibroin composite films for biomedical applications. In this study, urocortin expression was evaluated by both immunohistochemistry and reverse transcription-polymerase chain reaction, in human uterine tissues and cells at different phases of the menstrual cycle. Veterans underwent structured psychiatric diagnostic interview and completed self-report measures of combat exposure, posttraumatic stress disorder (PTSD), depression, and occurrence of head injury.

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Weight reduction programmes at a rehabilitation centre and a health centre based on group counselling and individual support: short- and long-term follow-up study. A truncated bone morphogenetic protein 4 receptor alters the fate of ventral mesoderm to dorsal mesoderm: roles of animal pole tissue in the development of ventral mesoderm. Quantification of insulin-like growth factor-I also manifests elevated insulin-like growth factor-I levels in silicotic rat bronchoalveolar lavage fluids which tend to increase with prolongation of silica exposure in vivo, but no alteration in insulin-like growth factor-I level can be found in sera. Synchrotron radiation circular dichroism spectroscopy of ribose and deoxyribose sugars, adenosine, AMP and dAMP nucleotides.

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In this study, snaR was identified as upregulated and to play a role in cancer progression of HER2-positive breast cancer cells. Gene transfer of endothelial nitric oxide synthase to the penis augments erectile responses in the aged rat. Value of prostatic specific antigen screening in prostatic cancer The interest in improving the definitions of asthma phenotypes and endotypes is growing, although these classifications do not always correlate with prognosis nor are always appropriate therapeutic approaches. Pseudoephedrine use among US children, 1999-2006: results from the Slone survey.

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Evaluation of a vessel-sealing device for use in laparoscopic ovariectomy in mares. Contribution to the interpretation of the inter- and parafollicular cells of the thyroid in various experimental conditions (observations by electron microscope) The different behavior for holes and electron transport is due to differing transport mechanisms. The effect of fluvoxamine and sertraline on the opioid withdrawal syndrome: a combined in vivo cerebral microdialysis and behavioural study. Evaluations for trans-epidermal water loss (TEWL), skin hydration and erythema were carried out at baseline, 0, 4, 8, 24, 48 and 72 hours after the treatment.

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Smad3 deficiency did not alter the response of bone marrow cells to TGF-beta1. Fibrous hamartoma tissues were surgically excised at the time of osteosynthesis from seven patients with congenital pseudarthrosis of the tibia associated with neurofibromatosis type 1. Developing cultural competence in the baccalaureate nursing student: a population-based project with the Hutterites.

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MST1 and MST2 are located in mitochondria and cytoplasm, respectively, as shown by immunoblot analysis of subcellular fractions and by green fluorescent protein (GFP) analysis. Modification of cycling biomechanics during a swim-to-cycle trial. This study demonstrates the close relationship between the epithelial cells and the immunocompetent cells in a rat periodontium, indicating a functional interrelationship. Non-pharmacologic interventions used to reduce spasticity include physiotherapy, occupational therapy, use of adaptive equipment, various orthopedic surgical procedures and neurosurgical procedures. The causative prions are found especially in neural tissues and spinal fluid, and in the case of vCJD, in lymphoreticular tissue.

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There has been a quiet revolution in the care of children with diabetes over the last decade. The effects of an exercise physiology program on physical fitness variables, body satisfaction, and physiology knowledge. Public Health Service and the Department of Health and Human Services provides a blueprint of health goals for the nation into the 21st century. There was transitory homonymous hemianopia (one patient), brief jerking of one arm (two patients), and affective (crying) reaction (three patients) after the end of a train of stimuli.

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Effects of cryopreservation on human sperm deoxyribonucleic acid integrity. Asymmetric Synthesis of Pyrrolidine-Containing Chemical Scaffolds via Tsuji-Trost Allylation of N-tert-Butanesulfinyl Imines. Donors were categorized by age, sex, and cumulative number of granulocyte donations. Vectors based on the adeno-associated virus (AAV) have attracted much attention as potent gene-delivery vehicles, mainly because of the persistence of this non-pathogenic virus in the host cell and its sustainable therapeutic gene expression. Weaning from mechanical oxybutynin er tab ventilation--the team approach and beyond.

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